Pituitary - adrenocortical function in morphine addicted rats

Comparison of post-operative pain in morphine-addicted and non-addicted rats

Post-operative pain and its management remains one of the most important issues in the field of surgery and health care system. On the other hand, opioid drug abuse has a large prevalence in Iran. Formalin test has been used as a method for assessing pain and analgesia in rats. In the present study, the post-operative pain in morphine addicted rats was compared with that of non-addicted ones us...

Short ACTH test in assessing hypothalamic-pituitary-adrenocortical function.

The adrenocortical response to the simple 30-minute ACTH stimulation test was compared with the hypothalamic-pituitary-adrenocortical (HPA) response to insulin-induced hypoglycaemia in 25 patients with various degrees of hypothalamic-pituitary malfunction. The correlations between the increase in plasma cortisol during insulin hypoglycaemia and that during ACTH stimulation (r = 0-66) and betwee...

Assessment of adrenocortical function in cases of pituitary tumour.

Behavioral and electrophysiological aspects of cognition in neonate rats lactated by morphine addicted mothers

Objective(s): In addition to genetic factors, environmental phenomena during postnatal age highly affect development and, in turn, function of the brain. The present work evaluates if morphine consumption during lactation period influences the spatial performances and synaptic plasticity in rats at neonatal period of age. Materials and Methods:</stron...

Morphine Decreased Peritoneal Adhesion in Addicted Male Rats after Abdominal Surgery

Introduction Peritoneal adhesions have been reported as an adverse side effect of surgery for more than a century and occur in 90-100% of cases. Postoperative adhesion formation results from a series of local events at the trauma site. Peritoneal injury by surgery, infection, or irritation initiates a local inflammatory reaction, exudation, and fibrin deposition into which white blood cells; ma...